13 Businesses for the Age of AI

Greg Isenberg· 25 min· 4,157 words· 19 min read· English ·Watch on YouTube

This is the full transcript of 13 Businesses for the Age of AI, published on YouTube by Greg Isenberg. Every paragraph carries the moment it was spoken, so you can click any line to jump straight to that point in the video, search the whole thing for a word, or copy it out.

0:00Today we're going to talk about the only businesses left to build in the agentic era. Yes, I think that there's only 13 businesses to be building in the world of agents. Now, I don't subscribe to the people who say there's going to be this permanent underclass and you just got to create businesses or else you're kind of messed up for the future. I don't think it's going to be as dire as that, but I do think that in you know, in a world where agents exist, abundance are going to exist, owning these assets, I mean, are going to put you just in a better position. So, today what are we going to

0:34do? We're going to go through the 13 businesses that are left to be built. By the end of this you're going to understand all 13 pretty well, [music] why why there's an opportunity, why they're going to exist in a world of agents, couple ideas. So, but you know, grab your coffee, grab your tea, strap in because hey, [music] this is the stuff that, you know, if you're in your teenager, if you're in 20s, your 30s, 50s, 70s, this is good stuff to know [music] because the world is changing and it is

1:06changing fast. [music]

1:15So, the first type of business that, you know, you'd want to own in an AI agent world is AI native service firms. What is that? Well, an AI native service firm firm is when the agents do more of the delivery. Now, I've seen people say AI native service firms is when they do all of the delivery. I don't believe that's the case. I think you can still have the agent doing 90% of the work and still be an AI native firm. So, as an example, you can create a bookkeeping firm for one type of business where, you know, you have client records, the agents prepare the books, and then the

1:53human reviews exceptions, and then you complete monthly books. And you charge for the completed job. It could be a a monthly fee, but it could also be, "Hey, every time we, you know, complete these books, it's going to cost XYZ." Um why is owning this business good? Well, it's high margin. Uh you don't need that many clients. Um the why now exists when you have uh you know, uh Astra, uh 5.5, um some of these great models that are

2:27are coming out soon. Um you know, you actually they, you know, could get this incredible amount of output. So, I'm really interested in AI-native service firms. I did a whole episode on one recently. I'll include it in the description um around creating a creative agency. So, you can imagine doing like a logos as a service or or ads as a service, these sorts of things. Really like these businesses, super high margin, uh and

2:54something I'm ideating actively around. The second is just generally offline businesses. Um you know, people Yes, it's an AI age, but we, you know, people actually want to pay to go and do something with other people. So, uh one example of this is um you know, this this company called Othership. I heard about them from the founder actually in Toronto where they started. Um and they've got this like neighborhood sauna club where there's you know, you walk into the sauna and it's like huge and there's other people and there's music uh and they, you know, there's someone who can help you do cold plunges and it's just this incredible

3:35environment and tea. Um they basically leveled up the experience of a communal sauna. And I think now more than ever uh you know, people want this sort of thing. And it's not cheap. It's really not. Um the visit itself could be, you know, I don't I don't remember exactly what it is, but it's it's not cheap. Um but it's an incredible experience and they sell a membership. So, I think businesses like this that, you know, are on to uh trends, um you know, here the trends are obviously are wellness, um community,

4:10um and you're just seeing them scale. They've been scaling in New York and I just I love these types of businesses, um especially ones that have a membership model. So, I think you're going to see a lot more like this. Um and you can run, you know, of course you can have agents do a lot of the admin, but the room, the experience is what people are buying. Now, the hard part about offline businesses, obviously, is that it costs a lot more money to start an offline business than an AI-native service firm, especially if you're creating an offline business in a place like Manhattan or Toronto, like place

4:46with high amount of real estate. So, um you know, how I think about offline businesses is, you know, what is the food cart version of uh or food truck. What is the food truck version of your business? What do I mean by that? If you're going to start a restaurant, sometimes the best thing to do is to start a food truck version of it because it's just so much cheaper, um and you can prove out that model that way. So, um the MVP, you know, what is the what does that look like? And I actually think I actually now that I'm remembering, I remember speaking to the founder about

5:21this, the first version of Othership was literally in the founder's backyard. He literally like made this in his backyard, and obviously that didn't cost too much money. He started inviting friends, community members, and then he decided to get uh a place. So, take it one step at a time. Third is distribution. So, we live in this world now where you prompt a few times and all of a sudden you basically have a startup, but getting people to the products that you're building or people are building is uh harder than ever, honestly. And my belief is that the price of reaching people is going to get higher and

6:06higher. And actually, if you take a step back and look at what people used to charge for, for example, a Facebook ad. In 2000 and you know, nine or whatever, when the Facebook ad platform came out, they were literally charging 5 cents a click. Now, the average click, uh you know, I don't I don't have the exact data in front of me, but we're talking a dollar, two dollars, like you know, even more than that. Three dollars, four dollars, five dollars, depending on who you're trying to target and which country you're trying to

6:35target. So, I think that owning organic audiences is so so so important, and I think that even be you know, before you end up, you know, if you end up wanting to create an offline business, if you end up wanting to create an AI native service for a firm, starting with the distribution, building organic audiences, the cool part about this is you can get paid to generate, you you know, useful niche information. You get paid by advertisers to basically build your audience, and then you go and build the products that they ask for. This is something I call the ACP funnel, audience community product. First, you start with the

7:13audience, then you build the community, then you build the product. Um this is something that, you know, is a business model. I think people who own multiple you know, meme pages, multiple uh YouTube channels, multiple uh uh Instagram audiences, those people are going to do well in this era. So, I think number three, distribution. The fourth, which is actually not talked about that often, is proprietary data sets. So, I think that uh what you're what you're starting to see is that data is just so valuable. Data is the new oil. Um you know, there's all these companies like Merch One, Micro One who um who are selling data to the big labs and

8:03are getting in you know, insane valuations, billions of dollars, hundreds of millions of ARR. It's absolutely insane. And so there's that that's the big idea you know, at the big idea like level which is basically pay people for data, get data that the big models don't have and then uh basically market up to the big labs, but if you're just a you know, solo founder and you don't want to go build something that big and you want to create a business that might generate a few million dollars a year is just how do you just get very useful information and that people cannot get by using

8:43their personal agents or um or going to chat GBT, that sort of thing. And I think thinking about that uh is a really really important thing. Um I think there's going to be this gold rush for getting and acquiring data. I think we're in the first inning of that and this is just a business that you know, if you own data you know, in this

9:05AI world, you're looking really good. The fifth is domain specific harnesses. Now, I feel like a lot of people throw the word harness around and like honestly, people don't really understand what it is. Um so, I'm going to take a second to explain to you in just as clear as I can what a harness really means and how is it different than a LLM model. So, um you know, you can think you can think of the model or I think of the model as basically the engine of the car. Um, how fast it goes, um, and I think of the harness as the tools it can

9:49access, the workflow rules, the memory, the checks. Basically everything around the the engine. Um, and if we use the car analogy, we're talking about like the body, we're talking about the steering wheel, we're talking about um, the floor mats, you're talking about the color of the car, the paint, you know, the electrical, everything else. That's the easiest way to explain it. It's not It's not a perfect way of explaining it. You know, I am missing a few things, but that's like the general way to think about. So, if you can take a general model and turn it into a system that understands how an industry works, for

10:26example, you know, the example I was using is the operating system for a freight brokerage agent, you know, you're going to be able to have a lot of value. You know, we talked about the gold rush and proprietary data sets. I think you're also witnessing now this gold rush around harnesses. I believe that

10:45harnesses are the new GPT wrapper. Two years ago, we saw a lot of people create GPT wrappers. Initially, for about 12 months, people were saying GPT wrappers were useless. People weren't going to weren't going to be able to create any sort of lasting value with it or any value with it. And we saw quite the opposite. The well, we saw a bunch of uh GPT wrappers go nowhere in the same way that, you know, startups 90% fail. But I think the top 10% a lot of what happened

11:17is they turned into harnesses. So, they were they had they started as a a wrapper focused on one model, and as that model got better, um, that service got better, but they started adding things like here. Like they started adding industry tools and workflow rules and memory and then they became harnesses. An example of that would be you saw a lot of that in the legal space, Harvey, spell spellbook, I

11:43think it's called. So I expect to see a lot more of that. I think there's a lot of opportunity here and by the way, comment in the on YouTube for if you ever want me to go deeper into any one of these, just let me know and I can create dedicated videos with some ideas and that sort of thing. And also, while you're at it, like this and if you're on Spotify or Apple, please rate rate it five stars cuz we got some a few low stars so from from back in the day. So let's try to get it up. The sixth is robotics and physical AI. So

12:23this one a lot of people think that it is so far away in the future that it's like the Jetsons. Just like really in the future, but I don't think people realize that we are like almost there. I saw this new product called Osmo. I think they raised like six or seven million dollars recently and they are literally doing window

12:47cleaning as a service. So building owners pay for clean windows and then you deploy and operate the equipment or they they deploy and operate the the equipment and it's just a beautiful business, right? The hard part is obviously building these companies, right? But I think that you're going to see a lot more robotics and physical AI and actually the best way to I saw a really good tweet by my friend Brian Norgard and he said I think the best way to sell software is by selling hardware and I think you're going to see a lot of that. So a lot more businesses like that and for the

13:26people listening who are like, I'm not going to go and create a robotics company. What do I know about, you know, all this PhD stuff. Well, I think there's going to be an opportunity for you to maybe buy a few and rent it to people, or buy, you know, if you're into sales, you can go and sell them. You know, there's a lot of opportunity. It doesn't necessarily mean you need to be an Elon Musk character to go and like figure out what these things are and build them. You can also be on the sales, marketing side, and I think there's going to be a ton of

13:59opportunity. Number six. Number seven, uh physical products with a fan following. Um so, this is the I'm sure a lot of you know that I love coffee, um and I'm a bit of a nerd like that. Um specialty coffee equipment is um an example of like people get like so nerdy about it, and they're willing to pay high prices for well-designed

14:29things. Um and when Fellow came out, like there was nothing like this. A lot of the This is um a kettle. So, a lot of the kettles didn't really feel like they were designed for coffee people. And then this came out, and it started, you know, that they started crushing it, and now they have a huge product suite of different um of different products. Like I got a uh Fellow grinder back there. By the way, not affiliated with with Fellow. Just just again, like a fan. Um and uh I think there's a ton of opportunity to just like create these niche products. I also think with

15:09um hard uh just AI, like for example, uh you know, Astra and the latest new models, you can actually design hardware and physical products That were too niche before, you can go and do that now. So if you have the insight for a particular fan following or particular ICP, you can go and buy I think the device is like the

15:37bamboo. It's a Chinese device and you can go and like prototype um some of these new products and then, you know, obviously mass produce it, sell it. Another friend of mine uh our friend of mine started something called the Minimal Company and those are phones that are focused on people who don't want to scroll and I think they they did millions of dollars on their uh Kickstarter. Again, that's like a fan following. I you know, Apple's not creating that product. So there's a lot of opportunity. I think there's a lot of pent-up demand for specific products here. um And especially the ones that can go viral in that niche. So if you have if

16:23you have if you really understand a niche that was a really good time. I really do want to do an episode around like physical products, how to use AI to create them. So hopefully you guys are into that. Um number eight, compute and energy. um We can't forget that every agent needs chips, electricity, cooling and somewhere to run. So if you own that scarce input um hey, that is a good place to be. Saw just the other week Crusoe raised 3.9 billion dollars for its vertically integrated AI infrastructure platform. um So you're just seeing that. I think uh Michael Dell's son uh is raising billions of dollars for his, you know,

17:11energy uh company. um You're just seeing people people need compute, people need energy. These are the scarce inputs of our time. So, if there's any way that you can go and uh be involved in some of these businesses, probably do pretty well. Number nine, health, longevity, uh and care. Uh I I've talked a lot about on the Startup Ideas podcast, on this podcast, about uh older adults. I think older adults are missing It's just like a an ICP that a lot of people, especially younger people, are not creating for, but they need products, they need services, um and there's, you know, any way we can make their lives happier and healthier,

17:59I think would be a great thing. So, I think there's tons of ideas, products, services, um that are actually high-quality, that have a high NPS, that are exceptional, that you could be creating, um and then also, from a service business perspective, care, uh there's a lot of opportunity there. Um help helping older adults, um and and just like owning agencies in that space, uh for example, caregivers and things like that. Lot here, um and uh obviously hard businesses to do, a lot of those service businesses to run, um but great great businesses, and also, you know, you're doing a good thing by caring for for folks. And then the

18:49longevity piece, I mean, I feel like Bryan Johnson really kicked off this whole, you know, don't die movement. Um he really Well, he didn't kick it off, he kind of tapped into it. He he He was like, "I'm the guy." Um so, you know, health, maybe that was Huberman, longevity, maybe that was uh

19:09Bryan Johnson. Um there's still opportunity to go and be the gal or guy in that space if you just, you know, I go down and niche niche down. But point is, there's a lot of opportunity here, a lot of business to be create to be created, and I think a lot of un a lot of demand to tap into. The 10th is marketplaces and social networks. Now, a lot of people are not creating these products and startups anymore. When I first came to Silicon Valley, uh it was just the thing. We're talking 2013, 2014, 2015, that era. You know, creating things like Uber, which matched, you know, drivers and

19:55customers. Creating things like Thumbtack, which was like services to find a handyman and and things like that. And social networks, Instagram, TikTok, things like that. Uh, the thing is I I On one hand, I love these businesses cuz if you're able to create it, you do truly have a moat. But liquidity, meaning making sure you have both the demand and supply at the same time, is an art. I feel like marketplaces and social network is more art than science in that

20:33way. But I think there's tons of opportunities right now. Mark Lou, who some of you know, had you know, created a marketplace around selling startups and buying startups, trustmr.com. So, you're starting to see people come back to marketplaces and social networks, but I feel like it's a great thing to own, co-own, be a part of if you can. Personal agents are going to want to access marketplaces, they're going to want to access social networks. The data that comes from both these things are really interesting. I love these businesses, so had to put it in there as well. I I just

21:05in general, just like real assets. Um so the example I have here is small industrial workshops rented to local trades. You know, in trades in general by the way, like electricians, cabinet makers, plumbers, um physical assets, warehouses, uh you know, industrial industrial warehouses, things like that. Uh we forgot, you know, we can't forget that, you know, you need a place to have a location, a property for a lot of the new world that we're entering in. So literally physical locations and real real assets, real estate, I think still going to be a really interesting business. Vertical agents, number 12. So just giving an agent responsibility for

21:52a recurring job in a specific industry. The example I have here is purchasing for indie restaurants. So you have checking stock, comparing supply offers, ask for approval, place the order. I feel like people have been building vertical agents for the last like 12 months, but I still think there's a ton of opportunity um to build like we talked about harnesses and to build uh agents. And last but not

22:19least is security. Uh people need security more than ever in the AI age. Now I'm talking about two types of security. I'm talking about software companies like one password. Uh I'm talking about, you know, companies like Cloudflare uh who have a lot of security AI features. I'm talking about, you know, the example I have here, agent access control for accounting firms that allow you to just read invoices and draft entries that would allow, you know, allow you to do that. Um but basically uh thinking about sensitive workflows and then working through firms' existing IT providers and just having access controls so that data doesn't get leaked

23:03and things don't get hacked and things like that. I think that's a one piece of it. Uh just security in the agentic era, things are going to get hacked. This is going to be more and more of a problem. You know, I think I wouldn't be surprised if one of the personal agent startups um or just agent startups, like there's like a a big a big hack security breach uh and things get put on the internet. I think that might happen. Um I think it's going to happen. I think it's actually it's it's it's going to happen more and more. So, people are going to want

23:39security and owning those assets and businesses are going to be great. And then like actually security in general, like I think there's like a Uber, forget the name of it, but it's like Uber for like you know, bodyguards and you know, you get a car and it's like bulletproof and stuff like that. I think there's going to be more of those businesses. People feel less and less

24:01secure. So, they're just going to want to pay for security in general. A lot of security businesses, I'm really interested. And that's that's what I'd want to own in this world. I mean, I'm not saying, like I said in the beginning, not saying to escape the permanent under crust, you need a own a piece of this, but I am saying these are the only businesses that are left. Owning a piece of these businesses are going to set you up. Um and this is where it's at. This is a map of the ones that I would pay attention to, the 13 ones,

24:37uh the best ones. Um and I hope that this has gotten your creative juices flowing. Um please do let me know. Uh I read every single comment. I reply to most on on YouTube. And thank you for giving me your time. Um I don't take that lightly. I I think it's amazing I can just come on here and be like, "Hey, I think that these are the 13 businesses uh left the only businesses left to build." And some of you are going to take that in and it's going to impact your lives. Um and that's really cool. So, thank you again. You're the best. I'm rooting for

25:15you and I'll see you next time.

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